KADIAN (MORPHINE SULFATE)
PAIN, CHRONIC, SEVERE
PAIN WITH OPIOID TOLERANCE
ANESTHESIA, GENERAL ADJUNCT, LOCAL ADJUNCT
Morphine sulfate is a strong analgesic used to relieve severe, acute pain or moderate to severe, chronic pain (e.g., in terminally ill patients). The drug is also used parenterally for preoperative sedation, as a supplement to anesthesia, and for analgesia during labor. Morphine sulfate is also available as a preservative-free injection (AstramorphÆ PF, DuramorphÆ PF, InfumorphÆ) that can be injected epidurally or intrathecally for relief of severe pain (neuraxial analgesia); administration of the drugby these routes reportedly provides pain relief for prolonged periods without attendant loss of motor, sensory, or sympathetic function.